10/7/2026
Vital Signs · mental-health

What happens in the brain when cannabis makes you anxious?

Filed by Dr. Iris Vale
What happens in the brain when cannabis makes you anxious?
Cannabinoids may intensify anxiety by removing a natural brake on specific neurons in the brain’s fear center, particularly during stressful situations. In mice, shutting down those neurons sharply reduced cannabinoid-related anxious behavior.
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Dr. Iris Vale
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What happens in the brain when cannabis makes you anxious? — Vital Signs