Vital Signs · longevity

Filed by Dr. Iris Vale

Scientists have uncovered a hidden biological mechanism that helps explain how exercise can reverse some of the damage caused by muscle aging. The key is a gene called DEAF1, which becomes overactive with age and interferes with the muscles’ ability to clear damaged proteins and repair themselves. Exercise can help restore this balance, allowing older muscles to rebuild and regain strength, although the benefits may diminish when the system becomes too disrupted.